Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1990-03-14
1993-10-12
Martinell, James
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435119, 43525233, 43525235, 4353201, 435 76, 935 9, 935 29, 935 72, 935 73, 935 75, C12N 1500, C12N 1511, C12P 1718
Patent
active
052524744
ABSTRACT:
There are disclosed plasmids containing DNA isolated from Streptomyces avermitilis, the microorganism which is used to prepare avermectin compounds, identified as pAT1, pVE650 pVE855, pVE859, pVE1446, pVE923, and pVE924 which contain the genetic information for the biosynthesis of the avermectins. Methods for the isolation of such plasmid and for the manipulation of the plasmids to alter the formation of the avermectin compound are also disclosed.
REFERENCES:
patent: 4703009 (1987-10-01), MacNeil et al.
The Extended Phenotype, 1982, Dawkins, Oxford University Press, Oxford, pp. 85, 86, and 287.
Hutchinson; Applied Biochemistry and Biotechnology 16: 169 (1987).
Murooka et al; Agric. Biol. Chem. 47: 1807 (1983).
Hopwood, et al Nature 314, pp. 642-644.
Schulman, et al, Jour. of Antib. 38 pp. 1494-1498 (1985).
Ruby, et al Sixth Annual Symposium on Actinomycetes Bio. pp. 279-280 (1985).
Ikeda, et al J. Bacteriol. 169, pp. 5615-5621 (1987).
Chater, et al EMBO Jour. 4, pp. 1893-1897 (1985).
Malpartida, et al Nature 309 pp. 462-464 (1984).
Schulman, et al Antimicrobial Agents and Chemotherapy 31 pp. 744 and 746 only (1987).
Fishman, et al Proc. Natl. Acad. Sci. USA 84 pp. 8248-8252 (1987).
Motamedi, et al Proc. Natl. Acad. Sci. USA 84 pp. 4445-4449 (1987).
McNeil, J. Microbiol. Methods 5 pp. 115-123 (1986).
Feitelson, et al J. Gen. Microbiol. 131 pp. 2431-2441 (1985).
Murakami, et al Mol. Gen. Genet. 205 pp. 42-50 (1986).
MacNeil, et al J. Industrial Microbiol. 2 pp. 209-218 (1987).
Chen, et al Bio/Technology 6 pp. 1222-1224 (1988).
Miller, et al Antimicrobial Agents and Chemotherapy 15 pp. 368-371 (1979).
Ruby et al, "Isolation and Characterization of Streptomyces Aremitilis Mutants Defective in the Methylation of the Avermectins"--Conference Paper (1980)--Abstract only.
Gewain Keith M.
MacNeil Douglas J.
MacNeil Tanya
Paress Philip S.
Ruby Carolyn L.
DiPrima Joseph F.
Martinell James
Merck & Co. , Inc.
Rose David L.
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