Cloning and use of the transaminase gene ilvE

Details Cloning and use of the transaminase gene ilvE Cloning and use of the transaminase gene ilvE

1990-08-13

1992-06-09

Peet, Richard C.

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

435 691, 435 712, 435 91, 435108, 4351721, 4351723, 4353201, 435849, 536 27, 935 6, 935 9, 935 14, 935 22, 935 24, 935 29, 935 33, 935 38, 935 59, 935 60, 935 61, 935 66, C12N 121, C12N 1552, C12N 1570

Patent

active

051206544

ABSTRACT:
The ilvE gene from the strain E. coli ATCC 11303 is suitable for achieving overproduction of the coded aliphatic transaminase and thus for preparing the branched-chain amino acids leucine, isoleucine and valine from the corresponding keto precursors.

REFERENCES:
Shimatake et al., Nature 292, pp. 128-131, 1981.
Kuramitsu et al., J. Biochem. 97, pp. 993-999 (1985).

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