Cloning and recombinant production of polistinae venom...

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S196000, C435S198000, C536S023200

Reexamination Certificate

active

07060265

ABSTRACT:
A unique clone of a Polistinae venom enzyme, recombinantly produced Polistinae venom enzymes, and methods of using the recombinant enzymes are provided. In a specific example, both phospholipase and hyaluronidase cDNA fromPolistes annularescontain apparent “intronic” sequences. In still a further enbodiment, genetic engineering permits the construction of the “intronic” sequences to yield a useful coding sequence for expression of mature Polistinae venom enzyme proteins.

REFERENCES:
patent: 5593877 (1997-01-01), King
patent: WO9400137 (1994-01-01), None
patent: WO9420623 (1994-09-01), None
Frohman, M.A. et al.; “Rapid Production of Full-Length CDNAs From Rare Transcripts: Amplification Using a Single Gene-Specific Oligonucleotide Primer”; Proceedings of the National Academy of Sciences of USA, US, National Academy of Science. Washington, vol. 85, 1998, pp. 8998-9002.
Kordis, D. and Gubensek, F.; “Ammodytoxin C Gene Helps to Elucidate the Irregular Structure of Crotaline Group II Phospholipase A2 Genes”;European Journal of Biochemistry, vol. 240, No. 1, Aug., 1996, pp. 83-90.
King, T.P. et al.; “Yellow Jacket Venom Allergens, Hyaluronidase and Phospholipase: Sequence Similarity and Antigenic Cross-Reactivity With Their Hornet and Wasp Homologs and Possible Implications for Clinical Allergy”;J. Allergy Clin. Immunol., vol. 98, No. 3, 1996, pp. 588-600.
Mueller, U. et al.; “Successful Immunotherapy With T-Cell Epitopes of Bee Venom Phospholipase A2 (PLA) in Patients With Bee Venom (BV) Allergy”;Journal of Allergy and Clinical Immunology, US, Mosby-Yearly Book, Inc., vol. 97, No. 1, Part 03, Jan. 1996, p. 426.
Soldatova, L. et al.; “Sequence Similarity of a Hornet (D. Maculata) Venom Allergen Phospholipase A1 With Mammalian Lipases”;Febs Letters, vol. 320, 1993, pp. 145-149.
Lu, G. et al.; “Sequence Identity and Antigenic Cross-Reactivity of White Face Hornet Venom Allergen, Aldo a Hyaluronidase, With Other Proteins”;Journal of Biological Chemistry, vol. 270, No. 9, 1995, pp. 4457-4465.
Hoffman, D.R.; “Allergens in Hymenoptera Venom. XXVI: The Complete Amino Acid Sequence of Two Vespid Venom Phospholipases”;International Archives of Allergy and Immunology, vol. 104, 1994, pps. 184-190.
King, T.P. et al.; “Murine T and B Cell Responses to Natural and Recombinant Hornet Venom Allergen Dol M 5.02 and its Recombinant Fragments”;Journal of Immunology, US, The Williams and Wilkins Co., Baltimore, vol. 154, No. 2, 1995, pp. 577-584.
Forsdyke, R.; “Conservation of Stem-Loop Potential in Introns of Snake Venom Phospholipase A2 Genes: An Application of FORS-D Analysis”;Molecular Biology and Evolution, vol. 12, No. 6, Nov. 6, 1995, pp. 1157-1165.
Justesen, A. et al.; “Analysis of Two Incompletely Spliced Arabidopsis cDNA Encoding Novel Types of Peroxidase”;Biochimica and Biophysica Acta, vol. 1443, Oct. 26, 1998, pp. 149-154.
Database EMBL Nucleotide and Protein Sequences, Sep. 7, 1999, Hinxton, GB, AC=AF174528. Polistes annularis hyaluronidase precursor mRNA, partial cds. Abstract.
King, T.P. et al.; “Wasp Venom Proteins: Phospholipase A1 and B1”;Archives of Biochemistry and Biophysics; 1984, vol. 230, No. 1, pp. 1-12.
Suggs, et al. PNAS, USA, 78(11);6613-6617, 1981.
Edman, et al. Eur. J. Biochem., 1:80-91, 1967.
King, et al., Archives of Biochem. Biophys., 230(1):1-12, 1984.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Cloning and recombinant production of polistinae venom... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cloning and recombinant production of polistinae venom..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cloning and recombinant production of polistinae venom... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3669802

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.