Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2008-05-13
2008-05-13
Devi, S. (Department: 1645)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S300000, C530S825000, C424S190100, C424S234100, C435S069300, C435S071100, C435S320100, C514S002600
Reexamination Certificate
active
07371821
ABSTRACT:
The inventive subject matter relates to a recombinant 110 kDa protein fromO. tsutsugamuchi, Karp, Kato and Gilliam strains and for a DNA expression system containing DNA encoding the 110 kDa protein ofO. tsutsugamuchi. The invention also relates to the use of these recombinant contructs in a formulation for the induction of a protective immune response againstO. tsutsugamuchiinvection using. The inventive subject matter also relates to a recombinant 110 kDaO. tsutsugamuchiprotein or 110 kDa fragments for the production of antigen for use in immunodiagnosistic asssays for scrub typhus.
REFERENCES:
patent: 2003/0165523 (2003-09-01), Ching et al.
Oaks et al. Infect. Immun. 55: 1156-1162, 1987.
Mierendorf et al. inNovations 1: 1-3, 1994.
Chao Chien-Chung
Ching Wei-Mei
Churilla Albert M.
Devi S.
Hemby, Jr. Joseph K.
The United States of America as represented by the Secretary of
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