Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-08-17
1998-08-11
Budens, Robert D.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 71, 435 79, 435 792, 435 793, 4241391, 4241461, 530350, 53038826, G01N 33543
Patent
active
057926204
ABSTRACT:
Human pancreatic islet cell glutamic acid decarboxylase (GAD), an autoantigen involved in the development of insulin-dependent diabetes mellitus (IDDM), has been cloned, sequenced and expressed by recombinant means. Recombinant human islet cell GAD polypeptides and antibodies specific to the GAD polypeptides can be used in methods of diagnosis and treatment, including use in immunoadsorptive therapy and the induction of immune tolerance.
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Foster Donald C.
Grubin Catherine E.
Hagopian William
Karlsen Allan E.
Lernmark Ake
Budens Robert D.
The Board of Regents of the University of Washington
ZymoGenetics Inc.
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