Cloning and expression of host-protective immunogens of IBDV

Chemistry: molecular biology and microbiology – Vector – per se

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435 693, 43525233, 4241851, 4242041, 530350, 536 234, 536 2372, C12N 121, C07H 2104, A61K 3912

Patent

active

058495754

ABSTRACT:
A recombinant DNA molecule comprising a nucleotide sequence substantially corresponding to all or a portion of IBDV RNA, particularly the IBDV RNA segment of approximately 3400 b.p. In particular, a DNA molecule coding for all or a part of at least one structural protein of IBDV, for example, the 32 Kd and/or the 41/37 Kd structural proteins. Synthetic peptides or polypeptides, and fused polypeptides, prepared by expression of host cells containing these DNA molecules are also disclosed.

REFERENCES:
patent: 5350575 (1994-09-01), Azad et al.
patent: 5614409 (1997-03-01), Azad et al.
Jagadish et al. 1990 Gene 95:179.
MacNeadie et al 1990 Vaccine 8:549.
Azad et al 1986 Virology 149:190.

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