Cloning and expression of early growth regulatory protein genes

Details Cloning and expression of early growth regulatory protein genes Cloning and expression of early growth regulatory protein genes

1988-09-26

1993-04-27

Ellis, Joan

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C07K 300, C07H 1512

Patent

active

052061523

ABSTRACT:
Disclosed are DNA sequences encoding novel DNA binding proteins implicated in regulation of early stages of cell growth. Illustratively provided are human and mouse origin DNA sequences encoding early growth regulatory ("Egr") proteins which include "zinc finger" regions of the type involved in DNA binding. Also disclosed are immunological methods and materials for detection of Egr proteins and hybridization methods and materials for detection and quantification of Egr protein related nucleic acids.

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