Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1995-11-15
2000-07-04
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
435 697, 435325, 4352523, 4353201, 536 231, 536 234, 536 235, C12N 1512, C12N 1570, C12N 1585
Patent
active
060837136
ABSTRACT:
The present invention relates to the cloning of .beta.APP-C100 receptor (C100-R), and genetically engineered host cells which express the C100-R. Such engineered cells may be used to evaluate and screen drugs and analogs of .beta.-APP involved in Alzheimer's Disease.
REFERENCES:
Leberer et al. The EMBO Journal 11 (1992) 4815-4824.
Rudinger In "Peptide Hormones" (Jun. 1976) ed. J.A. Parsons, University Park Press, Baltimore, pp. 1-7.
Kozlowski Michael R.
Manly Susan P.
Neve Rachael L.
Bristol--Myers Squibb Company
Caputa Anthony C.
Hayes Robert C.
McLean Hospital Corporation
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