Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-02-14
2006-02-14
Ulm, John (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S069100, C435S252300, C435S320100, C530S350000, C536S023500
Reexamination Certificate
active
06998244
ABSTRACT:
There is disclosed an isolated or substantially pure form of a nucleic acid molecule encoding a human 5-HT4(h)receptor, which 5-HT4(h)receptor preferably comprises the sequence illustrated in FIG.1B. Also provided by the invention are expression vectors incorporating said nucleic acid molecule in addition to transgenic cells, tissues or organisms transfected with the nucleic acid molecule.
REFERENCES:
patent: WO 94/14957 (1994-07-01), None
patent: WO 00/77199 (2000-12-01), None
Eckard Bender, Armelle Pindon, Irma van Oers, Yu-Bin Zhang, Walter Gommeren, Peter Verhasselt, Mirek Jurzak, Josee Leysen, and Walter Luyten, “Stucture of the Human Serotonin 5-HT(4) Receptor Gene and Cloning of a Novel 5-HT(4) Splice Variant” Journal of Neurochemistry, 2000, XP-000953119, pp. 478-483.
Olivier Blondel, Monique Gastineau, Yamina Dahmoune, Michel Langlois, and Rodolphe Fischmeister, Cloning, Expression and Pharmacology of Four Human 5-hydroxytryptamine(4) Receptor Isoforms Produced by Alternative Splicing in the Carboxyl Terminus, Journal of Neurochemistry, 1998, XP-000953121, pp. 2252-2261.
Ullmer, Christoph et al., “Expression of serotonin receptor mRNAs in blood vessels”; FEBS Letters 370 (1995) 215-221.
EP application 00 947 854.6-1223; Communication under 96(2) dated Aug. 7, 2005.
Bender Eckhard
Jurzak Mirek
Luyten Walter Herman Maria Louis
Pindon Armelle Nathalie Françoise
Van Oers Irma Petronella
Janssen Pharmaceutica N.V.
Ulm John
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