Cloned human cripto gene and applications thereof

Details Cloned human cripto gene and applications thereof Cloned human cripto gene and applications thereof

1994-11-10

1997-08-05

Myers, Carla J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 71, 435 74, 536 235, 536 2431, 536 2433, 436 64, 436 86, 935 8, 935 9, 935 77, 935 78, C12Q 168, C07H 2104, G01N 3353

Patent

active

056541406

ABSTRACT:
A new human gene designated as "CRIPTO" gene has been identified and cloned. CRIPTO gene products and derivatives thereof have been obtained and various utilities of the same have been described. Association of CRIPTO gene with cancers, such as colorectal cancer and breast carcinoma, has been indicated.

REFERENCES:
Ciccodicola et al. EMBO J. 8(7): 1987-1991, 1989.
Holt et al. P.N.A.S. 83: 4794-4798, 1986.
Weinberg, R.A. in "Onocgenes and the Molecular Origins of Cancer", ed R.A. Weinberg, CSH, 1989, pp. 314-315.
Zen, G. "Pharmaceutical Considerations in "Oligodeoxynuleotides, Antigene Inhibitors of Gene Expression, CRC Press, 1989, pp. 233-255.
Ciardiello, F. et al. Cancer Research 51: 1051-1054, 1991.

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