Cloned genomes of infectious hepatitis C viruses and uses thereo

Details Cloned genomes of infectious hepatitis C viruses and uses thereo Cloned genomes of infectious hepatitis C viruses and uses thereo

1998-01-27

2000-11-28

Schwartzman, Robert A.

Chemistry: molecular biology and microbiology

Virus or bacteriophage, except for viral vector or...

4353201, 435325, 435366, 435370, 435455, 536 2372, C12N 510, C12N 700, C12N 1551

Patent

active

061534218

ABSTRACT:
The present invention discloses nucleic acid sequences which encode infectious hepatitis C viruses and the use of these sequences, and polypeptides encoded by all or part of these sequences, in the development of vaccines and diagnostics for HCV and in the development of screening assays for the identification of antiviral agents for HCV.

REFERENCES:
patent: 5679342 (1997-10-01), Houghton et al.
Yoo et al. (1995) Transfection of a differentiated human hepatoma cell line (Huh 7) with in vitro-transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV. J. Virol. 69:32-38, Jan. 1995.
Honda et al. (1996) Structural requirements for initiation of translation by internal ribosome entry within genome-length hepatitis C virus RNA. Virology 222:31-42, Aug. 1996.
Yanagi et al, "Transcripts of a Chimeric cDNA Clone of Hepatitis C Virus Genotype 1b Are Infectious In Vivo", Virology, vol. 244, No. 1, Apr. 25, 1998, pp. 161-172.
Dash, S., et al. (1997). Am. J. Pathol. 151, 363-373.
Fausto, N. (1997). Am. J. Pathol. 151, 361.
Kolykhalov, A.A., et al. (1997). Science 277, 570-574.
Yanagi, M. et al. (1997). Proc. Natl. Acad. Sci. USA. 94, 8738-8743.
Farci, P., et al. (1996). Proc. Natl. Acad. Sci. USA 93, 15394-15399.
Inchauspe, G. et al. (1991) Proc. Natl. Acad. Sci. U.S.A., 88:10292-10296.
Kolykhalov, A.A., A.A., Feinstone, S.M. and Rice, C.M. (1996). J. Virol. 70, 3363-3371.
Ogata, N. et al (1991) Proc. Natl. Acad. Sci. U.S.A.., 88:3392-3396.
Okamoto, H., et al. (1992) Virology 190, 894-899.

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