Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Reexamination Certificate
2007-04-10
2007-04-10
Priebe, Scott D. (Department: 1633)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
C424S204100, C424S205100, C424S189100, C514S04400A, C435S320100, C435S325000, C435S370000, C435S455000
Reexamination Certificate
active
09662454
ABSTRACT:
The present invention discloses nucleic acid sequences which encode infectious hepatitis C viruses and the use of these sequences, and polypeptides encoded by all or part of these sequences, in the development of vaccines and diagnostics for HCV and in the development of screening assays for the identification of antiviral agents for HCV.
REFERENCES:
patent: 5679342 (1997-10-01), Houghton et al.
patent: 6127116 (2000-10-01), Rice et al.
patent: 0 516 270 (1992-12-01), None
patent: WO 97/08310 (1997-03-01), None
patent: WO 98/39031 (1998-09-01), None
Byoung J. Yoo et al, Transfection of a Differentiated Human Hepatoma Cell Line (Huh7) with In Vitro-Transcribed Hepatitis C Virus (HCV) RNA and Establishment of a Long-Term Culture Persistently Infected with HCV, Jan. 1995, p. 32-38, vol. 69, No. 1.
Nelson Fausto, Editor-in-Chief, Replication of Hepatitis C Virus in Tissue Culture: A Potential Breakthrough in Need of Cofirmation, vol. 151, No. 2, Aug. 1997.
Forns et al, The chllenge of developing a vaccine against hepatitis C virus, J Hepatology, 2002, vol. 37, pp. 684-695.
Rice, Hepatitis C: Progress toward New Therapies from Third Annual PHRI Symposium, published 2006 and downloaded Jan. 23, 2006.
Yanagi et al, “Transcripts of a Chimeric cDNA Clone of Hepatitis C Virus Genotype 1b Are Infectiousin Vivo”, Virology, vol. 244, No. 1, Apr. 25, 1998, pp. 161-172.
Dash et al, “Transfection of HepG2 Cells with Infectious Hepatitis C Virus Genome”,AmericanJournal of Pathology, vol. 151, No. 2, Aug. 1997, pp/ 363-373.
Fausto, “Replication of Hepatitis C Virus in Tissue Culture: A Potential Breakthrough in Need of Confirmation”, American Journal of Pathology, vol. 151, No. 2, Aug. 1997, p. 361.
Kolykhalov et al, “Transmission of Hepatitis C by Intrahepatic Inoculation with Transcribed RNA”, Science, vol. 277, No. 5325, Jul. 1997, pp. 570-574.
Yanagi et al, “Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfedted into the liver of a chimpanzee”,Proc. Natl. Acad. Sci.USA, vol. 94, Aug. 1997, pp. 8738-8743.
Yoo et al, “Transfection of a Differentiated Human Hepatoma Cell Line (Huh7) with In Vitro-Transcribed Hepatitis C Virus (HCV) RNA and Establishment of a Long-Term Culture Persistently Infected with HCV”,Journal of Virology, vol. 69 , No. 1, Jan. 1995, pp. 32-38.
Farci et al, “Prevention of Hepatitis C virus infection in chimpanzees by hyperimmune serum against thehypervariable region 1 of the envelope 2 protein”,Proc. Natl. Sci. USA, vol. 93, Dec. 1996, pp. 15394-15399.
Inchauspe et al, “Genomic structure of the human prototype strain H of hepatitis C virus: Comparison with American and Japanese isolates”,Proc. Natl. Sci USA, vol. 88, No. 22, Nov. 1991, pp. 10292-10296.
Kolykhalov et al, “Identification of a Highly Conserved Sequence Element at the 3′ Terminus of Hepatitis C Virus Genome RNA”,Journal of Virology, vol. 70, No. 6 Jun. 1996, pp. 3363-3371.
Ogata et al, “Nucleotide sequence and mutation rate of the H strain of hepatitis C virus”,Proc.Natl. Acad. Sci. USA, vol. 88, Apr. 1991, pp. 3392-3396.
Okamoto et al, “Genetic Drift of Heptatis C Virus during an 8.2-Year Infection in a Chimpanzee: Variability and Stability”, Virology, vol. 190, 1992, pp. 894-899.
Honda et al, “Structure Requirements for Initiation of Translation by Internal Ribosome Entry within Genome-Length Hepatitis C Virus RNA”, Virology, vol. 222, 1996, pp. 31-42.
Kolykhalov et al, “Hepatitis C Virus-Encoded Enymatic Activites and Conserved RNA Elements in the 3′ Nontranslated Region Are Essential for Virus Replication In Vivo”,Journalof Virology, vol. 74, No. 4, Feb. 2000, pp. 2046-2051.
Lindenbach, B.D. et al. (2006) “Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro” PNAS 103(10): 3805-3809.
Yu M-YW, Bartosch B, Zhang P, Guo Z-P, Renzi PM, Shen L-M, Granier C, Feinstone SM, Cosset F-L, Purcell RH. Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma.PNAS USA2004;101(20):7705-7710.
Meunier JC, Engle RE, Faulk K, Zhao M, Bartosch B, Alter H, Emerson SU, Cosset FL, Purcell RH, Bukh J. Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1.PNAS USA2005;102(12):4560-4565.
Bassett, SE, Guerra B, Brasky K, Miskovsky E. Houghton M. Klimpel GR, Lanford RE. Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection.Hepatology2001:33:1479-1487.
Major ME. Mihalik K, Puig M. Rehermann B, Nascimbeni M, Rice CM, Feinstone SM. Previously infected and recovered chimpanzees exhibit rapid responses that control hepatitis C virus replication upon rechallenge.Journal of Virology2002:76(13):6586-6595.
Lanford RE. Guerra B, Chavez D. Bigger C, Brasky KM, Wang XH, Ray SC, Thomas DL. Cross-genotype immunity to hepatitis C virus.Journal of Virology2004;78(3):1575-1581.
Weiner AJ, Paliard X, Selby MJ, Medina-Selby A. Coit D, Nguyen S, Kansopon J, Arian CL, Ng P, Tucker J, Lee CT, Polakos NK. Han J, Wong S, Lu HH, Rosenberg S, Brasky KM, Chien D, Kuo G, Houghton M. Intrahepatic gentic inoculation of hepatitis C virus RNA confers cross-protective immunity.Journal of Virology2001;75(15):7142-7148.
Bukh J, Thimme R, Satterfield WC, Meunier JC, Spangenberg HC, Forns X, Chang KM, Emerson SU, Chisari FV, Purcell RH. Persistence of HCV after homologous monoclonal re-challenge is associated with emergence of virus variants. In Jilbert AR, Grgacic EVL, Vickery K, Burrell CJ, Cossart YE, eds.Proceedings of the 11thInternational Symposium on Viral Hepatitis&Liver Disease.Australian Centre for Hepatitis Virology 2004:375-377.
Yanagi M, Purcell RH, Emerson SU, Bukh J. Hepatitis C virus: An infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras.Virology1999;262(1):250-263.
Okamoto H, Mishiro S, Tokita H, Tsuda F, Miyakawa Y, Mayumi M. Superinfection of chimpanzees carrying hepatitis C virus of genotype II/1b with that of genotype III/2a or I/1a.Hepatology1994;20:1131-1136.
Thimme R, Bukh J, Spangenberg HC, Wieland S, Pemberton J, Steiger C, Govindarajan S, Purcell RH, Chisari FV. Viral and immunological determinants of hepatitis C virus clearance, persistance, and disease.PNAS USA2002;99(24)15661-15668.
Major ME, Dahari H, Mihalik K. Puig M, Rice CM, Neumann AU, Feinstone S. Hepatitis C Virus kinetics and host responses associated with disease and outcome of infection in chimpanzees.Hepatology2004;39(6):1709-1720.
Bigger CB. Braky KM, Lanford RE. DNA microarray analysis of chimpanzee liver during acute resolving hepatitis C virus infection.Journal of Virology2001;75(15):7059-7066.
Su A, Pezacki JP, Wodicka L, Brideau AD, Supekova L, Thimme R, Wieland S, Bukh J, Purcell RH, Schultz PG, Chisari FV. Genomic analysis of the host response to hepatitis C virus infection.PNAS USA2002;99(24):15669-15674.
Bukh Jens
Emerson Suzanne U.
Purcell Robert H.
Yanagi Masayuki
Knobbe Martens Olson & Bear LLP
Marvich Maria
Priebe Scott D.
United States of America, as represented by the Secretary, Depar
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