Cloned DNA sequences related to the entire genomic RNA of human

Details Cloned DNA sequences related to the entire genomic RNA of human Cloned DNA sequences related to the entire genomic RNA of human

1993-10-07

1996-08-13

Fleisher, Mindy

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 2104

Patent

active

055457266

ABSTRACT:
A method for diagnosing an HIV-2 (LAV-II) infection and a kit containing reagents for the same is disclosed. These reagents include cDNA probes which are-capable of hybridizing to at least a portion of the genome of HIV-2. In one embodiment, the DNA probes are capable of hybridizing to the entire genome of HIV-2. These reagents also include polypeptides encoded by some of these DNA sequences.

REFERENCES:
patent: 4629783 (1986-12-01), Cosand
Jakobovits et al., "A Discrete Element 3' of Human Immunodeficiency Virus 1 (HIV-1) and HIV-2 mRNA Initiation Sites Mediates Transcriptional Activation by an HIV trans Activator," Molecular and Cellular Biology, 8, No. 6, 2555-2561 (1988).
Clavel et al., "Isolation of a New Human Retrovirus from West African Patients with AIDS," Science, 233, 343-346 (1986).
Chakrabarti et al., "Sequence of Simian Immunodeficiency Virus from Macaque and its Relationship to Other Human and Simian Restrovirusus," Nature, 328, 543-547 (1987).
Arya, et al., "New Human and Simian HIV-Related Retrovirusis Posses Functional Transactivator (tat) Gene," Nature 328, 548-550 (1987).

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