Cloned DNA encoding a UDP-GalNAc: Polypeptide, N-acetylgalactosa

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide

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435 701, 435 711, 435 712, 435 72, 435 74, 435 97, 435440, 435455, 435471, 435476, C12N 1554, C12P 2100

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active

060965126

ABSTRACT:
The present invention relates to a method for the isolation and expression of a glycosyltransferase enzyme for use in the synthesis of oligosaccharide or polysaccharide structures on glycoproteins, glycolipids, or as free molecules. The gene coding for the enzyme N-acetylgalactosaminyltransferase and the polypeptide sequence of the acceptor peptide for the enzyme N-acetylgalactosaminyltransferase have been isolated and used for the control of glycosylation of a protein.

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