Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Enzymatic production of a protein or polypeptide
Patent
1993-11-24
1998-01-20
Caputa, Anthony C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Enzymatic production of a protein or polypeptide
435 91, 4351723, 4352351, 4352402, 4352523, 4352551, 43525421, 536 232, 536 235, 530350, 935 9, 935 18, 935 32, 935 41, 935 57, 935 61, 935 71, C12N 1552, C12N 1563, C12N 1565, C12N 1570
Patent
active
057100144
ABSTRACT:
A cloned cDNA containing complete coding sequence for the expression of a protein with all properties of the precursor to human procathepsin L is described. All of the protein's major domains, including the pre, pro, and carboxyterminal extensions are represented in the full length cDNA sequence of the present invention.
REFERENCES:
Joseph et al. J. Clin. Invest. 81:1621-1629 May 1988.
Yang etal Nucl. Acids Res vol. 12 pp. 837-843 (1984).
Woods etal. J. Clin. Invest. vol. 74 pp. 634-638 (1984).
Masar et al Biochem J. vol. 240 pp.373-377 (1986).
Suggs et al Proc Natl Acad Sci USA vol. 78 pp. 6613-6617 (1981).
Partnoy et al J. Biol Chem vol. 261 pp 1497-14703 (1986).
Masor et al Chemical Abstracts vol. 105 p. 360 Abstract No. 22175a (1886).
Maniatis, T. et al Molecular Clarity, A Laboratory Manual Cold Springs Herbor Laboratory CSH; NY (1982).
Ueda, K et al Proc Nat'l Acad Sci USA vol. 84 pp. 3004-3008 (1987).
Gottsman, "Transformantion-dependent Secretion of a Low Molecular Weight . . . ", Proc. Natl. Acad. Sci. USA, 75:2767-2771 (Jun. 1978).
Doherty, et al., "Malignant Transformation and Tumor Promoter . . . ", Molecular and Cellular Biology, 5:466-473 (Mar., 1985).
Troen, et al., "Sequence and Expression of the cDNA for MEP (Major Excreted Protein) . . . ", Biochem J., 731-735, Great Britain (1987).
Gal Susannah
Gottesman Michael M.
Smith Spencer
Caputa Anthony C.
The United States of America as represented by the Department of
LandOfFree
Cloned cDNA for human procathepsin l. does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cloned cDNA for human procathepsin l., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cloned cDNA for human procathepsin l. will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-724528