Clone of a nucleotide sequence encoding a protein having two fun

Details Clone of a nucleotide sequence encoding a protein having two fun Clone of a nucleotide sequence encoding a protein having two fun

1998-03-18

1999-03-30

Carlson, Karen Cochrane

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

536 232, C12N 948, C07H 2104

Patent

active

058887962

ABSTRACT:
A nucleotide sequence which encodes a protein which is substantially similar to eukaryotic initiation factor-2 (eIF-2) associated glycoprotein (p67) and also has methionine amino peptidase activity. The encoded protein may facilitate protein synthesis by protecting eIF-2 from phosphorylation and prepare the protein for critical cellular role by removing N-terminal methionine.

REFERENCES:
patent: 4865974 (1989-09-01), Ben-Bassat et al.
patent: 5470719 (1995-11-01), Meng et al.
patent: 5608036 (1997-03-01), Meng et al.
Arfin et al., Cotranslational processing and protein turnover in eukaryotic cells, Biochemistry 27 (21):7979-7984.
Ball et al., J. Mol Biol. 79:531-537 (1973).
Bazan et al., Sequence and structure comparison suggest that methionine aminopeptidase, prolidase, aminopeptidase P, and creatinase share a common fold, Proc. of the Natl. Acad. of Sci. USA 91:2473-2477 (1994).
Ben-Bassat et al., J. Bacteriol. 169:751-757 (1987).
Chang et al., J. Biol Chem. 265:19892-19897 (1990).
Chang et al., J. Biol. Chem. 267:8007-8011 (1992).
Duronio et al., Science 243:796-800 (1989).
Gordon et al., J. Biol. Chem. 266:8647-8650 (1991).
Huang et al., Biochemistry 26:8242-8246 (1987).
Kendall et al., J. Biol. Chem. 267:20667-20673 (1992).
Kozak, J. Biol. Chem. 26:19867-19870 (1991).
Li et al., Proc. Natl. Acad. Sci USA 92:12375-12361 (1995).
Li et al., Molecular cloning of a human complementary DNA encoding an initiation factor-2 associated protein (p67), Biochimica et Biophysica Acta 1260:333-336 (1995).
Meinnel et al., Methionine as translation start signal: A review of the enzymes of the pathway in Escherichia coli, Biochimie 75:1061-1075.
Miller et al., Proc. Natl. Acad. Sci. USA 84:2718-2722 (1987).
Moerschell et al., J. Biol. Chem. 265:19638-19643 (1990).
Ngo et al., Computational complexity, protein structure prediction, and the Levinthal paradox. In: The Protein Folding Problem and Tertiary Structure Prediction, Eds. Merz et al., Birkhauser, Boston, MA 491-495 (1994).
Ray et al., Biochemistry 32:5151-5159 (1993).
Roderick et al., Biochemistry 32:3907-3912 (1993).
Wu et al., Cloning and characterization of complementary DNA encoding the eukaryotic initiation factor 2-associated 67-kDa protein (p67), J. Bio. Chem. 268(15):10796-10801 (1993).

Affiliated with

Also associated with

Rating

Clone of a nucleotide sequence encoding a protein having two fun does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Clone of a nucleotide sequence encoding a protein having two fun, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Clone of a nucleotide sequence encoding a protein having two fun will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1213842