Clock gene promoter

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism

Reexamination Certificate

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Details

C435S325000, C536S024100, C536S023100, C800S003000, C800S014000, C800S018000

Reexamination Certificate

active

06977157

ABSTRACT:
The present invention discloses a Period2 gene promoter, a construct containing the promoter and a reporter gene, a cell containing the construct, a transgenic animal harboring the construct, and a method for screening a substance which controls expression or oscillatory expression of a biological clock gene. The screening method uses the above cell, a suprachiasmatic nucleus section or peripheral tissue of the above transgenic animal or the above transgenic animal.

REFERENCES:
patent: 6475744 (2002-11-01), Reppert et al.
patent: WO 01/07654 (2001-02-01), None
patent: WO 01/36618 (2001-05-01), None
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