Clinical procedure for measuring lipoprotein cholesterols

Details Clinical procedure for measuring lipoprotein cholesterols Clinical procedure for measuring lipoprotein cholesterols

1977-09-21

1978-08-08

Prescott, Arthur C.

Chemistry: electrical and wave energy

Processes and products

Electrostatic field or electrical discharge

204180G, 204299EC, G01N 2726

Patent

active

041055217

ABSTRACT:
An electrophoresis method of determining the concentration of high density lipoprotein (HDL) cholesterol in body fluids and simultaneously determining the concentrations of very low density lipoprotein (VLDL) and low density lipoprotein (LDL) cholesterols in the fluid. The method includes applying a small sample of the fluid to an electrophoresis support medium, applying a direct current across the medium, applying a developing substrate to the electrophoresed lipoproteins and quantitatively determining the concentration of each lipoprotein cholesterol. This method does permit direct and simultaneous measurement of each lipoprotein cholesterol fraction while eliminating precipitation of each fraction as required by the prior art.

REFERENCES:
patent: 3607695 (1971-09-01), Schneider
patent: 3759773 (1973-09-01), Dwyer et al.
patent: 3808118 (1974-05-01), Golias
patent: 3873433 (1975-03-01), Seidel et al.

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