Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing
Reexamination Certificate
2007-09-17
2010-02-23
Jones, D L (Department: 1618)
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
C424S001110, C424S001650, C424S001690, C424S009400
Reexamination Certificate
active
07666392
ABSTRACT:
The present application is directed to radiolabeled cyclic polypeptides, pharmaceutical compositions comprising radiolabeled cyclic polypeptides, and methods of using the radiolabeled cyclic polypeptides. Such polypeptides can be used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
REFERENCES:
patent: 1 733 742 (2006-12-01), None
patent: WO 2006/030291 (2006-03-01), None
Haubner et al., “Noninvasive imaging of alpha(v)beta3 integrin expression using 18F-labeled RGD-containing glycopeptides and positron emission tomography”, Cancer Research Mar. 1, 2001, vol. 61, No. 5, pp. 1781-1785.
Chen et al., “MicroPET imaging of brain tumor angiogenesis with 18F-labeled PEGylated RGD peptide”, European Journal of Nuclear Medicine and Molecular Imaging, Aug. 2004, vol. 31. No. 8, pp. 1081-1089.
Cai et al., “A thiol-reactive 18F-labelingn agent, N-[2-(4-18F-fluorobenzamido)ethy peptide-based tracer for PET imaging of alpha v beta 3 integrin expression”, Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, Jul. 2006, vol. 47, No. 7, pp. 1172-1180.
Zhang et al., “Quantitative PET imaging of tumor integrin alphavbeta3 expression with 18F-FRGD2”, Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, Jan. 2006, vol. 47, No. 1, pp. 113-121.
Poethko et al., “Two-step methodology for high-yield routine radiohalogenation of peptides: 18F-labeled RGD and Octreotide Analogs”, Journal of Nuclear Medicine, Society of Nuclear Medicine, Reston, VA, vol. 45, No. 5, May 2004, pp. 892-902.
Wu et al., “microPET imaging of glioma integrine {alpha}v{beta}3 expressioin using (64)Cu-labeled tetrameric RGD peptide”, Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, Oct. 2005, vol. 46, No. 10, pp. 1707-1718.
Poethko et al., “Chemoselective pre-conjugate radiohalogenation of unprotected mono- and multimeric peptides via oxime formation”, Radiochim ACTA, vol. 92, 2004, pp. 317-327.
Marik et al, “Click for PET: rapid preparation of [18F] fluoropeptides using Cul catalyzed 1,3-dipolar cycloaddition”, Tetrahedron Letters, Elsevier, Amsterdam, NL, vol. 47, Jul. 31, 2006, pp. 6681-6684.
Kolb et al., “Application of Click Chemistry to the development of COX-2 and CA-II inhibitors”, Abstracts of Papers American Chemical Society, vol. 231, Mar. 2006, pp. 403-MEDI.
Rijkers et al., “Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry”, Chemical Communications—Chemcom, Royal Society of Chemistry, GB, Aug. 19, 2005, pp. 4581-4583.
Chen et al., “MicroPET and autoradiographic imaging of breast cancer alphav-integrin expression using 18F- and 64CU-labeled RGD peptide”, Bioconjugate Chemistry, ACS, Washington, DC, vol. 15, No. 1, 2004, pp. 41-49.
Dijkgraaf et al., “Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes”, Organic & Biomolecular Chemistry Mar. 21, 2007, vol. 5, No. 6, pp. 935-944.
Sirion et al., “An efficient F-18 labeling method for PET study: Huisgen 1,3-dipolar cycloaddition of bioactive substances and F-18-labeled compounds”, Tetrahedron Letters, Elsevier, Amsterdam, NL, vol. 48, No. 23, Jun. 4, 2007, pp. 3953-3957.
Kuijpers et al, “Preparation and evaluation of glycosylated arginine-glycine-aspartate (RGD) derivatives for integrine targeting”, Bioconjugate Chemistry Nov.-Dec. 2007, vol. 18, No. 6, pp. 1847-1854.
Li et al., “Click chemistry for (18)F-labeling of RGD peptides and microPET imaging of tumor integrin alphavbeta3 expression”, Bioconjugate Chemistry Nov.-Dec. 2007, vol. 18, No. 6, pp. 1987-1994.
Christian W. Tornøe and Morten Meldal, “Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions on Solid-Phase” poster presentation, Jun. 11, 2001, Second International and Seventeenth American Peptide Symposium held by the American Peptide Society, San Diego, California.
Michal Lebl and Richard A. Houghten, “Peptides the Wave of the Future Proceedings of the Second International and the Seventeenth American Peptide Symposium”, Dec., 2001, pp. 263-264, American Peptide Society, San Diego, California.
Katumitu Hayakawa, Shoko Minami, and Sumio Nakamura, “Kinetics of the Oxidation of Ascorbic Acid by the Copper(II) Ion in an Acetate Buffer Solution”, Bulletin of the Chemical Society of Japan, vol. 46, pp. 2788-2791 (1973).
Chen Kai
Karimi Farhad
Kolb Hartmuth C.
Liang Qianwa
Padgett Henry Clifton
Jones D L
Kendall Peter L.
Siemens Medical Solutions USA , Inc.
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