Cleavable oligonucleotide arrays

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

Reexamination Certificate

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C435S287200, C536S025300

Reexamination Certificate

active

11284495

ABSTRACT:
Oligonucleotide arrays having features that include cleavable oligonucleotides are disclosed, as well as methods of making such arrays. Methods of synthesizing an oligonucleotide on a surface of a substrate are described.

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Pon et al., Linker phosphoramidite reagents for the attachment of the first nucleoside to underivatized solid-phase supports. Nucleic Acids Research 32(2) :623-631 (2004).
Pease et al., Light-generated oligonucleotide arrays for rapid DNA sequence analysis. PNAS 91 : 5022-5026 (1994).

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