Cleaning efficiency testing method and apparatus for a...

Liquid purification or separation – Processes – Including controlling process in response to a sensed condition

Reexamination Certificate

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C210S791000, C210S108000, C210S143000, C073S038000, C073S040000

Reexamination Certificate

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07320760

ABSTRACT:
A method and an apparatus are provided for testing the efficiency of a cleaning procedure for a filter in a filtering system. After the cleaning procedure of the filter, the filter pores contain a fluid. The system is pressurized, and a decay in pressure over a predetermined time period is measured. Based on the pressure decay, it is determined whether or not the cleaning procedure has been effective; a pressure decay smaller than a predetermined threshold value indicates that the cleaning procedure has not been effective.

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Brantley et al., “Integrity Testing of Sterlizing Grade Filters,” Pall Ultrafine Filtration Company, 1997.
“Validation Guide for the ‘Paltronic’ FFE04 Filter Integrity Test Instrument,” Pall Process Filtration Limited, England.
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Brantley et al., “Integrity Testing of Sterlizing Grade Filters, ” Pall Ultrafine Filtration Company, 1997.
Ramstorp et al., “Integritetstestning Av Sterilfilter, ” Colly Company AB, 1989, pp. 15-18.

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