Clavulanic acid salts and their preparation from the tertiary bu

Details Clavulanic acid salts and their preparation from the tertiary bu Clavulanic acid salts and their preparation from the tertiary bu

1981-12-24

1984-06-12

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D49804

Patent

active

044540698

ABSTRACT:
This invention provides a novel process for the preparation of clavulanic acid and pharmaceutically acceptable salts and esters thereof which process utilizes the preparation of the tertiary-butylamine salt of clavulanic acid optionally in the form of an acetone solvate and subsequently converting said salt into the desired product.

REFERENCES:
patent: 4144242 (1979-03-01), Fleming et al.
patent: 4244965 (1981-01-01), Howorth et al.
Beecham II, Chem. Abs. 90, 109963, (6-22-78).

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