Clavulanic acid derivatives their preparation and use

Details Clavulanic acid derivatives their preparation and use Clavulanic acid derivatives their preparation and use

1980-05-13

1983-02-08

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

2602453, C07D49804, A61K 3142

Patent

active

043729622

ABSTRACT:
The compounds of the formula (I): ##STR1## and pharmaceutically acceptable salts and in-vivo hydrolysable esters thereof wherein X is a sulphur atom or SO or SO.sub.2 group and R is a hydrogen atom or an alkyl group of 1 to 6 carbon atoms have been found to be .beta.-lactamase inhibitors and antibacterial agents. Their preparation and use is described.

REFERENCES:
patent: 4215128 (1980-07-01), Howarth
"IUPAC Nomenclature", pp. 475-477.
Cherry et al., Chem. Abs. 88, 6861v, (1977).
Cherry et al., Chem. Ab. 58, 190803b, (1978).

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