Clathrate compound

Details Clathrate compound Clathrate compound

1990-08-07

1992-02-25

Robinson, Allen J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514726, A01N 3104, A01N 4380

Patent

active

050914006

ABSTRACT:
2,2'-Bis(.alpha.-hydroxydiphenylemthyl)biphenyl of formula: ##STR1## Clathrate compound is composed of the above compound as the host compound and a microbicide, 5-chloro-2-methyl-4-isothiazolin-3-one as the guest compound. The compound is formed such that, where diphenic acid is reacted with an alcohol for diesterification and then reacted with a Grignard reagent comprising a phenylmagnesium halide.

REFERENCES:
patent: 4996220 (1991-02-01), Sekikawa et al.
Neugebauer et al., J. Organometallic Chem., vol. 228(2), pp. 107-118 (1982).
Gilman, J.A.C.S., vol. 77, pp. 6380-6381 (1955).

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