Class of seco bis-indolic compounds which can be used as drugs a

Details Class of seco bis-indolic compounds which can be used as drugs a Class of seco bis-indolic compounds which can be used as drugs a

1980-07-09

1982-08-31

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602444, 546 51, A61K 31475, C07D51904

Patent

active

043472494

ABSTRACT:
The invention relates to new chemical compounds.
They are compounds corresponding to formula Ia. ##STR1## in which: R'.sub.3 represents a hydrogen atom or a hydroxy radical; R'.sub.5 represents a hydrogen atom or a hydroxy radical; or R'.sub.3 and R'.sub.5 together represent an epoxy bridge or a double bond; R".sub.5 represents a hydrogen atom or an ethyl radical; R'.sub.7 and R'.sub.8 are the same or different and represent a hydrogen atom or a methyl, hydroxymethylene, alkoxymethylene, aryloxymethylene, aminomethylene, monoalkyl or dialkyl aminomethylene, acylmethylene, arylaminomethylene, hydroxyethyl aminomethylene, alkylthiomethylene, aryloxythiomethylene or cyanomethylene radical; R.sub.1 represents a hydrogen atom or an alkyl, formyl or acyl radical: R.sub.2 represents a hydrogen atom or an alkoxy radical; R.sub.7 represents an alkanoyloxy radical, the broken line representing an optional double bond.
These compounds can be used as drugs.

REFERENCES:
patent: 4122081 (1978-10-01), Thompson et al.
patent: 4144237 (1979-03-01), Kutney
Kutney et al., Heterocycles, vol. 9, No. 4, pp. 493-497 (1978).
Kutney et al., Heterocycles, vol. 11, pp. 69-73 (1978).
Potier et al., C. R. Seances Soc. Biol. Ses. Fil., vol. 173, No. 2, pp. 414-424 (1979).
Mangeney et al., J. Org. Chem., vol. 44, No. 22, pp. 3765-3768, (10/26/79).
Mangeney et al., Tetrahedron, vol. 35, No. 15, pp. 2175-2179 (10/13/79).

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