Class microfiber histamine assay device

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic

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436518, 4352871, 435810, 435962, 435 71, 4352879, 4352884, 422 57, 422 58, 422 61, 427180, 427189, 427196, 427215, 427220, G01N 33552, G01N 33543, G01N 3349

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active

054686504

ABSTRACT:
A histamine diagnostic assay device is provided in which glass microfibers treated with a polar organic polymer are deposited onto a carrier and used to selectively bind histamine in a sample. The polar organic polymer reduces the affinity of the glass microfibers for interfering components of the sample while substantially retaining the histamine-binding capacity. Preferably, the glass microfibers are provided as a conglomerate with the polar organic polymer. An agent which induces the release of histamine from cells in the sample may be included in the device.

REFERENCES:
patent: 4592956 (1986-06-01), Gaa et al.
patent: 4794090 (1988-12-01), Parham et al.
patent: 4869875 (1989-09-01), Skov et al.

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