Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1993-05-03
1995-01-31
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 2, 514 8, 514 16, 530300, 530324, 530328, A61K 3702, C07K 706
Patent
active
053858883
ABSTRACT:
Methods and compositions are provided for regulating surface membrane receptor response by modulating the interaction between an MHC Class I antigen and the surface membrane receptor. Various techniques may be employed for enhancing or reducing the interaction between the Class I antigen and surface membrane receptor, e.g., enhancing production of the Class I antigen.
REFERENCES:
patent: 5073540 (1991-12-01), Olsson
Due, C., et al., P.N.A.S. (USA) 83:6007-6011 (Aug. 1986), "The major histocompatibility complex class I heavy chain as a structural subunit of the human cell membrane insulin receptor: implications for the range of biological functions of histocompatibility antigens".
Fehlmann, M., et al., P.N.A.S. (USA) 82:8634-8637 (Dec., 1985), "Molecular association between major histocompatibility complex class I antigens and insulin receptors in mouse liver membranes".
Gilman, A. G., et al., The Pharmacological Basis of Therapeutics, 8th edition, pp. 1468-1470 (1990).
Kittur, D., et al., P.N.A.S. (USA) 84:1351-1355 (Mar., 1987), "Insulin binding to human B lympoblasts is a function of HLA haplotype".
Lafuse, W., et al., Biochemistry 1:49-54 (1980), "Interaction of the mouse major histocompatibility complex, H-2, on liver adenylate cyclase activity and on glucagon binding to liver cell membranes".
Paul, W. F. (ed), Fundamental Immunology, 2d edition (1989), pp. 652-653.
Phillips, M., et al., P.N.A.S. (USA) 83:3474-3478 (May, 1986, "Class I histocompatibility antigens and insulin receptors: evidence for interactions".
Robbins Pathological Basis of Disease (R. S. Cotran, et al., eds.), 4th edition (1989), pp. 994-1001.
Ruoslahti, E., et al. in Synthetic Peptides in Biology and Medicine, pp. 191-197 (1985), Alitalo, et al (editors), Elsevier Science Publishers B. V. (Biomedical Division), the Netherlands.
Schreiber, A. B., et al., J. Cell Biol. 98:725-731 (Feb., 1984), "Interaction between major histocompatibility complex antigens and epidermal growth factor receptors on human cells".
Simonsen, M., et al., Ann. Immunology (Inst. Pasteur) 134D, pp. 85-92 (1983), "Possible roles of compound membrane receptors in the immune system".
Goodenow Robert S.
Olsson Lennart
Cunningham Thomas
Nucker Christine M.
Rowland Bertram I.
The Regents of the University of California
LandOfFree
Class I MHC modulation or surface receptor activity does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Class I MHC modulation or surface receptor activity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Class I MHC modulation or surface receptor activity will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1102226