Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Reexamination Certificate
2005-08-09
2005-08-09
Borin, Michael (Department: 1631)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
C530S412000, C530S419000, C514S772000
Reexamination Certificate
active
06927282
ABSTRACT:
Protein suspensions comprising soluble and insoluble components are purified via flocculation with anionic polymers, such as polyacrylamides, potato starch, or modified cellulose. The procedure improves the efficiency of solid/liquid separations and can minimize or eliminate the requirement for centrifugation and/or filtration in large scale biotechnological processes. The method is particularly well suited for the purification and clarification of protein suspensions containing soluble somatotropin monomer using polyacrylamide and polysaccharide flocculants.
REFERENCES:
patent: 3695999 (1972-10-01), Forgione et al.
patent: 3956519 (1976-05-01), Evans et al.
patent: 4013555 (1977-03-01), Davis
patent: 4055469 (1977-10-01), Snoke et al.
patent: 4208282 (1980-06-01), Becker
patent: 4271028 (1981-06-01), Marfurt et al.
patent: 4382028 (1983-05-01), Paget
patent: 4511502 (1985-04-01), Builder et al.
patent: 4599390 (1986-07-01), Fan et al.
patent: 4634673 (1987-01-01), Johnson et al.
patent: 4645829 (1987-02-01), Ho
patent: 4652630 (1987-03-01), Bentle et al.
patent: 4761472 (1988-08-01), Schultze
patent: 4942035 (1990-07-01), Churchill et al.
patent: 5047511 (1991-09-01), Mehrotra
patent: 5182369 (1993-01-01), Storrs et al.
patent: 5413720 (1995-05-01), Miller
patent: 5543058 (1996-08-01), Miller
patent: 5551316 (1996-09-01), Savage
patent: 5773588 (1998-06-01), Owsley et al.
patent: 5929027 (1999-07-01), Takama et al.
patent: 5986073 (1999-11-01), Storrs et al.
patent: 57273 (1982-08-01), None
patent: 581 002 (1994-02-01), None
patent: 98/28336 (1998-07-01), None
Oechslein et al. International Journal of Pharmaceutics (1996), 139(1,2), 25-32.
F.A.P Garcia. (Chapter 12—Protein Purification), InRecovery Process for Biological Materialsedited by John F. Kennedy and Joaquin M. S. Cabral. 1993 John Wiley & Sons Ltd. pp. 355-367.
Halverson, F., Panzer, H.P., Kirk-Othmer Encycl. Chem. Technol., 3rdEd. (1980), vol. 10. 489-523. Editor(s) Grayson, Martin: Eckroth, David. Publisher: Wiley, New York, N.Y.
Database CaPlus, DN97:180612, EP 57273 (Nov. 1981).
Chivers Mark L.
Cibulskas Algird S.
Bonner Grace L.
Borin Michael
Cytec Technology Corp.
Howrey Simon Arnold & White , LLP
Monsanto Technology LLC
LandOfFree
Clarification of protein precipitate suspensions using... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Clarification of protein precipitate suspensions using..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Clarification of protein precipitate suspensions using... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3502034