Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1984-12-18
1987-06-30
Naff, David M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
426 36, 426 56, 426 63, 435219, 435815, 435816, C12N 964, C12N 950, A23C 1904, A23L 131
Patent
active
046770690
ABSTRACT:
This invention relates to three enzymes, their isolation from the viscera of bivalves, e.g. the surf clam or cherrystone clam, their characterization and uses. The first two are carboxyl proteinases having molecular weights of about 77,200 and about 36,700 and display activity similar to mammalian D-cathepins. The third is a thiol proteinase having a molecular weight of about 17,400 and displays activity similar to mammalian B-cathepins. In addition to attaching various substrates, the enzymes coagulate cheese milk and tenderize meat.
REFERENCES:
Characterization and Select Applications of Proteolytic Enzymes Extracted and Purified with Clam Viscera; Ph. D. Thesis of Hung-Chang Chen, dated Aug. 1984.
Reid and Rauchert, 1970, Comp. Biochem. and Physiol., 35:689-695.
Reid and Rauchert, 1972, Comp. Biochem. and Physiol., 41A:887-895.
Cockburn and Reid, 1980, Comp. Biochem. and Physiol., 65B:275-281.
Reid and Rauchert, 1976, Comp. Biochem. and Physiol., 54B:467-472.
Dumitru et al, 1977, Revue Roumaine Biochem., 14:95-100.
Dumitru et al, 1978, Comp. Biochem. and Physiol., 59B:81-85.
Jordachescu et al, 1978, Comp. Biochem. and Physiol., 61B:119-122.
Dumitru et al, 1975, Revue Roumaine Biochem., 12:159-165.
Reid, 1978, Veliger, 20:260-265.
Sakai et al, 1979, Comp. Biochem. Physiol., 62B:269-273.
Reid, 1977, Comp. Biochem. Physiol., 59A:573-575.
Noda et al, 1982, Agric. Biol. Chem., 46:1565-1569.
Barrett and Kirschke, 1981, Methods in Enzymology, 80:535-581.
Barrett, 1977, Proteinases in Mammalian Cells and Tissues, Chapter 4, Elsevier/N. Holland Biomed. Press.
Barrett, 1973, Biochem. J., 131:809-822.
Barrett, 1977, Proteinases in Mammalian Cells and Tissues, Chapter 5, Elsevier/N. Holland Biomed. Press.
Dingle et al, 1971, Biochem. J., 123:1-13.
Yago et al, 1975, J. Biolog. Chem., 250:4749-4754.
Sapolsky et al, 1972, J. Biolog. Chem., 247:2069-2076.
Penny et al, 1974, J. Sci. Fd. Agric., 25:703-708.
Penny et al, 1980, Dev. Meat Sci., 1:115-143.
Schwartz et al, 1977, Biochem. J., 167:811-820.
Etherington et al, 1977, Acta Biol. Med. Germ., 36:1555-1563.
Bird et al, 1977, Acta Biol. Med. Germ., 36:1587-1604.
Chen et al, J. Food Science, 51(1):71-75 and 78, 1986.
Chen et al, J. Food Science, 51(3):815-820 and 825, 1986.
Chen Hung-Chang
Zall Robert R.
Cornell Research Foundation Inc.
Naff David M.
LandOfFree
Clam derived proteinases does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Clam derived proteinases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Clam derived proteinases will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-447580