Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1985-03-15
1986-06-10
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
435169, A61K 3574, C12P 106
Patent
active
045942480
ABSTRACT:
CL-1577-B.sub.4 compound is derived by the solvolysis under anhydrous conditions of either CL-1577A compound or CL-1577B compound, obtained from the fermentative action of a purified strain of Actinomycete designated ATCC 39363 under aerobic conditions.
CL-1577-B.sub.4 compound is a potent antimicrobial agent, possessing activity against a number of gram-positive and gram-negative bacteria, yeasts, and fungi. In addition, the compound exhibits in vivo activity against the P388 murine leukemia cell line and in vitro activity against the L1210 murine leukemia cell line.
A method of making the compound as well as pharmaceutical compositions and methods for their use are also disclosed.
REFERENCES:
patent: 4335108 (1982-06-01), Argoudelis et al.
French James C.
Hokanson Gerard C.
Wilton John H.
Goldberg Jerome D.
Janssen Jerry F.
Warner-Lambert & Company
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