Citrullimycines, a process for their production and their...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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Details

C435S132000, C435S886000, C546S313000

Reexamination Certificate

active

06930130

ABSTRACT:
The present invention relates to novel active compounds named Citrullimycines, which are obtainable by cultivation ofStreptomycessp. ST 101396 (DSM 13309), and to their pharmaceutically acceptable salts and derivatives. The present invention further relates to a process for the production of the Citrullimycines, to the microorganismStreptomycetessp. ST 101396 (DSM 13309), to the use of the Citrullimycines and their pharmaceutically acceptable salts and derivatives as pharmaceuticals, for example as inhibitors of the neurotensin receptor, and to pharmaceutical compositions comprising Citrullimycines or a pharmaceutically acceptable salt or derivative thereof.

REFERENCES:
patent: 5252472 (1993-10-01), Grabley et al.
March, J., Advanced Organic Synthesis, 4thEdition, pp. 393-396, 1213 (1992).
Remington's Pharmaceuticals Sciences, 17thEdition, Mack Publishing Co., (Alfonso R. Gennaro, editor), pp. 1418-1419 (1989)..

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