Cisplatin analogs for cancer treatment

Details Cisplatin analogs for cancer treatment Cisplatin analogs for cancer treatment

1997-03-17

1999-07-13

Wilson, James O.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 46, 514492, 536 221, 536 2781, 424489, 556136, A61K 3128, A61K 3170, A61K 3324

Patent

active

059226897

ABSTRACT:
This invention comprises the synthesis and the use of two cisplatin analogs whereby (C.sub.10 H.sub.13 N.sub.5 O.sub.5) is guanosine. The stoichiometric ratio between cisplatin and guanosine may be 1:1 or 1:2. The complexes are to be used in cancer treatment, they may also be used to treat AIDS patients.

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Miller et al., Inorg. Chem., vol. 24, pp. 2421-2425, (1985).
Hollis et al., Chemical and Biological Properties of a New Series of cis-Diammineplatinum(II) Antitumor Agents Containing Three Nitrogen 32, 128-136.

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