Cis-platinum (II) amine lactate complexes

Details Cis-platinum (II) amine lactate complexes Cis-platinum (II) amine lactate complexes

1979-06-20

1981-06-02

Sneed, Helen M. S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424287, C07F 1500

Patent

active

042710855

ABSTRACT:
Cis-Platinum(II) amine lactate complexes are prepared by reaction of the appropriate platinum(II) amine chloride complex with silver lactate. These complexes possess pronounced anti-tumor activity and low toxicity and thus have high therapeutic indices. They are also highly soluble in water.

REFERENCES:
patent: 4115418 (1978-09-01), Gale et al.
patent: 4140707 (1979-02-01), Cleare et al.
Ridgway et al., J. of Clinical Hemotology and Oncology, 7, No. 1, p. 220, (1976).
Cleare et al., Bioinorganic Chemistry, V2, pp. 187-210, (1973).
Speer et al., J. of Clinical Hemotology and Oncology, 7 (3), p. 856, (1977).
Schwartz et al., Cancer Treatment Reports, V61 (8), pp. 1519-1525, (1977).
Marx, Science vol. 192 (424), pp. 774-775, (1976).
Cleare, Coordination Chemistry Reviews, vol. 12, pp. 349-404, (1974).
Connors et al., Platinum Coordination Complexes in Cancer Chemotherapy, Springer Verlag, N.Y., pp. 1-199, (1974).

Affiliated with

Also associated with

Rating

Cis-platinum (II) amine lactate complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cis-platinum (II) amine lactate complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cis-platinum (II) amine lactate complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1864501