Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-09-16
2008-09-16
Stockton, Laura L. (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C514S396000, C514S397000
Reexamination Certificate
active
10867154
ABSTRACT:
The present invention provides compounds according to formula Ihaving the designations provided herein, and pharmaceutically acceptable salts and esters thereof. These compounds inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity.
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Seung Hoon Cheon et al, Archives of Pharmacal Research, XP009036613,vol. 20, No. 2, pp. 138-143 (1997).
Haley Gregory Jay
Kong Norman
Liu Emily Aijun
Simonsen Klaus B.
Vu Binh Thanh
Hoffmann-La Roche Inc.
Johnston George W.
Rocha-Tramaloni Patricia S.
Stockton Laura L.
Wildman David E.
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