Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1993-04-02
1997-02-18
Elliott, George C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4351723, 4353201, 536 231, C12N 1511, C12N 1549, C12N 1563, C12N 1585
Patent
active
056041144
ABSTRACT:
Cis-acting repression sequences which are able to provide a cis-acting inhibitory effect on the expression of a gene when placed downstream of the gene in its untranslated message are dislcosed. Cis-acting anti-repression sequences which can relieve the cis-acting repression in the presence of the art gene product are also disclosed. These sequences correspond to a sufficient number of nucleotides from the HIV-I, HIV-2, STLV-3 or HTLV-IV genomes to provide the repression or anti-repression effects. The use of the sequences in vectors and systems to control the expression of a desired gene product is also described.
REFERENCES:
patent: 4935372 (1990-06-01), Haseltine et al.
Sodroski, et al., Nature 321:412-417 (1986).
Rosen, et al., Cell 41:813-823 (1985).
M.H. Malim et al (1989) Proc. Natl. Acad. Sci. USA 86:8222-8226.
M. Guyader et al (1987) Nature 326:662-669.
V. Hirsch et al (1987) Cell 49:307-319.
P. J. Dillon et al (1990) J. Virol. 64(9):4428-4437.
B. R. Cullen et al (1988) J. Virol. 62:2498-2501.
Goh Wei C.
Haseltine William A.
Rosen Craig A.
Sodroski Joseph G.
Terwilliger Ernest
Conlin David G.
Dana-Farber Cancer Institute
Eisenstein Ronald I.
Elliott George C.
Railey II Johnny F.
LandOfFree
Cis-acting repression sequences, cis-acting antirepression seque does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cis-acting repression sequences, cis-acting antirepression seque, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cis-acting repression sequences, cis-acting antirepression seque will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1601905