Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1995-08-23
1998-06-16
Rories, Charles C. P.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
435 6, 435 691, 435 913, 435 9152, 4351721, 4353201, 435325, 435375, 435410, 424450, 536 231, 536 241, 514 44, C12N 500, C12N 1563, C12N 1579, C12Q 168
Patent
active
057669031
ABSTRACT:
The present invention relates to a product and process for producing polypeptides, such products including a circular RNA having a ribosome binding site that engages an eukaryotic ribosome and cells transformed with such circular RNA. Circular RNA is produced by linking the 5' and 3' ends of a desired linear RNA sequence, and such constructs can be used to produce desired amounts of polypeptides when such constructs are translated either in vitro or in vivo. The present invention also relates to the use of circular RNA as a pharmaceutical agent to treat cells and animals involved in a disease.
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Chen Chang-you
Sarnow Peter
Rories Charles C. P.
University Technology Corporation
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