Chemistry: molecular biology and microbiology – Vector – per se
Reexamination Certificate
2005-12-20
2005-12-20
Lacourciere, Karen A. (Department: 1635)
Chemistry: molecular biology and microbiology
Vector, per se
C435S069100, C435S325000, C435S455000, C536S023100
Reexamination Certificate
active
06977174
ABSTRACT:
A circular DNA molecule, useful for gene therapy, comprising at least one nucleic acid sequence of interest, characterized in that the region allowing the replication thereof has an origin of replication with a functionality in a host cell that requires the presence of at least one specific protein foreign to said host cell. A method for preparing same, cells incorporating said DNA molecules and uses thereof in gene therapy are also described.
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Crouzet Joël
Soubrier Fabienne
Centelion
Finnegan Henderson Farabow Garrett & Dunner LLP
Gibbs Terra C.
Lacourciere Karen A.
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