Circuit for defining the dye dilution curves in vivo and in vitr

Details Circuit for defining the dye dilution curves in vivo and in vitr Circuit for defining the dye dilution curves in vivo and in vitr

1974-06-30

1978-06-13

Nelms, David C.

Radiant energy

Photocells; circuits and apparatus

Photocell controlled circuit

356 39, G01N 2128

Patent

active

040951170

ABSTRACT:
The invention concerns a circuit for the determination of the concentration of any component of a liquid containing three different components having different optical properties, for the determination of the concentration sum of all components and of one other component, for the determination of the product and of the quotient which is formed by the third component, and for the calculation of the blood volume per minute of the heart. One or more light sources, a light sensing element, an optical filter and a lens are disposed in the circuit, and also power supply circuits and control circuits. To these are added a signal converting unit or a sensing system operating on three wavelengths other than the isobestic points or on a range containing these points, containing optical measurement channels, and measuring on the transmission or reflection principle.
The signals delivered by the three-channel sensor or by the signal converter, as the case may be, are processed by logarithmatic circuits. The logarithmating circuits are connected to channel amplifiers, and to the latter are connected subtraction circuits and multiplication circuits.
By means of the electronics of suitable construction it is possible to determine in vivo and in vitro both the change with time of the concentration of the dye placed in the blood at any point in the circulatory system, and the volume of the blood.

REFERENCES:
patent: 3715601 (1973-02-01), Tucker
patent: 3770349 (1973-11-01), Legorreta-Sanchez
patent: 3851156 (1974-11-01), Green
patent: 3969024 (1976-07-01), Hashizume et al.
patent: 3972614 (1976-08-01), Johansen et al.

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