Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1997-03-27
1998-12-22
Geist, Gary
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
560 21, 5483315, 544332, C07C24100, C07C20500, C07D23344, C07D23902
Patent
active
058522107
ABSTRACT:
The present invention relates to a class of compounds represented by the Formula I ##STR1## or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the .alpha..sub.v .beta..sub.3 integrin.
REFERENCES:
patent: 5523302 (1996-06-01), Cain et al.
J. Am. Chem. Soc. (1983), 105(6), pp. 1697-1698. Wasserman, `Total synthesis of chaenorhine.`
Chen Barbara B.
Chen Helen Y.
Clare Michael
Docter Stephen H.
Khanna Ish Kumar
Davis Brian J.
G. D. Searle & Co.
Geist Gary
Kovacevic Cynthia S.
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