Cinnamic acid derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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560 21, 5483315, 544332, C07C24100, C07C20500, C07D23344, C07D23902

Patent

active

058522107

ABSTRACT:
The present invention relates to a class of compounds represented by the Formula I ##STR1## or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the .alpha..sub.v .beta..sub.3 integrin.

REFERENCES:
patent: 5523302 (1996-06-01), Cain et al.
J. Am. Chem. Soc. (1983), 105(6), pp. 1697-1698. Wasserman, `Total synthesis of chaenorhine.`

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