Cinnamamide derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514471, 514521, 514538, 514562, 514563, 514615, 514616, 558393, 549321, 560 39, 560 45, 562426, 562444, 564150, 564158, 564170, A61K 31165, C07C23311

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active

052946436

ABSTRACT:
Novel cinnamamide derivatives and the salts thereof are provided. An antihyperlipidemic composition is also provided. The composition comprises an active ingredient which is at least one selected from the group consisting of the above-mentioned cinnamamide derivative and the pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 4616086 (1986-10-01), Witte et al.
"Studies on Styrene Derivatives. II. Synthesis and Anti-Inflammatory Activity of 3,5-Di-Tert-Butyl-4-Hydroxystyrenes", Ikuo Katsumi, et al., Chemical and Pharmaceutical Bulletin, vol. 34, No. 4, (Apr. 1, 1986), Tokyo JP, pp. 1619-1627.
"3,5-Di-Tert-Butyl-4-Hydroyxcinnamamide Derivatives as Cardiotonics and Their Preparation", Fuse Yoshihide, et al. , Chemical Abstracts, vol. 110 No. 1, (Jan. 2, 1989), p. 719; col. 1; ref. No. 7874M, Columbus, Ohio, USA.
"Preparation of 3,5-Di-Tert-Butyl-4-Hydroxycinnamamide Derivatives as Antinflammatory", Ooe Takanori, et al., Chemical Abstracts, vol. 109, No. 21, (Nov. 21, 1988), p. 675; col. 1; Ref. No. 190042E, Columbus, Ohio USA.
"3,5-Di-Tert-Butyl-4-Hydroxycinnamamide Derivatives Containing Heterocycles", Chemical Abstracts, vol. 105, No. 13, (Sep. 29, 1986), p. 682; col. 2; Ref. No. 115081F, Columbus, Ohio, USA.
"Preparation of Quinolin-2-One Derivatives as Psychotropics, Antihypertensives, Antiiflammatories", Chemical Abstracts, vol. 111, No. 13, (Sep. 25, 1989), p. 651; col. 2; ref. No. 115059D, Columbus, Ohio, USA.

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