Cinnamamide derivative

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514255, 544360, 544386, 544390, 544393, 544394, 544395, 544399, 544400, 544401, A61K 31495, C07D295104, C07D40104

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active

053526775

ABSTRACT:
Cinnamamide derivatives and the salts thereof are provided. An antihyperlipidemic composition is also provided. The composition comprises an active ingredient which is at least one selected from the group consisting of the above-mentioned cinnamamide derivative and the pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 4616086 (1986-10-01), Witte et al.
Witte et al. Chem. Abstracts, vol. 99, No. 13; 105277t (1983).
"Studies of Styrene Derivatives. II. Synthesis and Anti-Inflammatory Activity of 3,5-Di-Tert-Butyl-4-Hydroxystyrenes", Ikuo Katsumi, et al., Chemical and Pharmaceutical Bulletin, vol. 34, No. 4, Apr. 1, 1986, Tokyo JP, pp. 1619-1627.
"3,5-Di-Tert-Butyl-4-Hydroxycinnamamide Derivatives As Cardiotonics and Their Preparation", Fuse Yoshihide, et al., Chemical Abstracts, vol. 110, No. 1, Jan. 2, 1989, pp. 719; col. 1, ref. No. 7874M, Columbus, Ohio, USA.
"Preparation of 3,5-Di-Tert-Butyl-4-Hydroxycinnamamide Derivatives as Anti-Inflammatory", Ooe Takanori, et al., Chemical Abstracts, vol. 109, No. 21, Nov. 21, 1988, pp. 675; col. 1; ref. No. 190042E, Columbus, Ohio USA.
"3,5-Di-Tert-Butyl-4-Hydroxycinnamamide Derivatives Containing Heterocycles", Chemical Abstracts, vol. 105, No. 13, Sep. 29, 1986, pp. 682; col. 2; ref. No. 115081F, Columbus, Ohio USA.
"Preparation of Quinolin-2-One Derivatives as Psychotropics, Antihypertensives, Antiflammatories", Chemical Abstracts, vol. 111, No. 13, Sep. 25, 1989, pp. 651; col. 2; ref. No. 115059D, Columbus, Ohio, USA.

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