Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-07-20
1985-08-27
Schwartz, Richard A.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548342, A61K 31415, C07D23364
Patent
active
045379009
ABSTRACT:
The invention relates to a new crystal modification of N-methyl-N'-{2-[(5-methylimidazol-4-yl)-methylthio]-ethyl}-N"-cyanoguanidi ne (cimetidine), a histamine H-2 receptor antagonist having the Formula (I) ##STR1## as well as to a process for preparing same. In the description, this new modification is named N-methyl-N'-{2-[(5-methylimidazol-4-yl)-methylthio]-ethyl}-N"-cyanoguanidi ne Z (cimetidine Z).
REFERENCES:
Prodic-Kojic, B., et al., Gazz. Chim. Ital., 109, 535 (1979).
Benke Bela
Csongor Eva
Deutsch nee Juhasz Ida
Domany Gyorgy
Farkas nee Kirjak Maria
Richter Gedeon Vegyeszeti Gyar R.T.
Schwartz Richard A.
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