CIDE-B polypeptides

Details CIDE-B polypeptides CIDE-B polypeptides

2006-07-25

2006-07-25

Myers, Carla J. (Department: 1634)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C530S323000, C536S023500

Reexamination Certificate

active

07081515

ABSTRACT:
The present invention relates to a purified or isolated polynucleotide encoding human CIDE B protein, the regulatory nucleic acids contained therein, polymorphic markers thereof, and the resulting encoded protein, as well as to methods and kits for detecting this polynucleotide and this protein. The present invention also pertains to a polynucleotide carrying the natural regulatory regions of the CIDE B gene which is useful, for example, to express a heterologous nucleic acid in host cells or host organisms as well as functionally active regulatory polynucleotides derived from said regulatory regions.

REFERENCES:
patent: 5314819 (1994-05-01), Yamada et al.
patent: 6348573 (2002-02-01), Nunez et al.
patent: WO 93/16178 (1993-08-01), None
patent: WO 97/01572 (1997-01-01), None
patent: WO 99/55134 (1999-11-01), None
Inohara, et al.; “CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor”; The EMBO Journal, vol. 17, No. 9, pp. 2526-2533, 1998; XP-002133431; Oxford University Press.
Inohara, et al.; “CIDE, a novel family of cell death activators with homology to the 45 kDa subunit to the DNA fragmentation factor”; The EMBO Journal, vol. 17, No. 9, pp. 2526-2533, 1998; XP-000882759; Oxford University Press.
Database EMBL 'Online!; accession No. A1051238; Strausberg; “NCI/CGAP, tumor gene index: . . . similar to . . . cell death-inducing DNA fragmentation factor, alpha subunit-like affector B”; XP-002133432, abstract.
Database EMBL 'Online!; accession No. AW024578; Sep. 14, 1999; Strausberg; “NCI/CGAP, tumor gene index: . . . similar to . . . cell death-inducing DNA fragmentation factor, alpha subunit-like effector B.”; XP-002133433; abstract.
Xiong, et al; “Biallelic markers in genetics studies of human diseases: their power, accuracy, and density in population-based linikage analyses”; American Journal of Human Genetics (Oct. 1997), vol. 61, No. 4, Suppl., pp. A301; 47th Annual Meeting of the American Society of Human Genetics, Baltimore MD, XP-000852591.
Kruglyak, Leonid; “The use of a genetic map of biallelic markers in linkage studies”; Nature Genetics, vol. 17, Sep. 1977, p. 21-4; XP-000882279.
Database EMBL 'Online!; accession No. p56198/ID FS27—mouse; Nov. 1, 1997; Danesch, et al.; “Fat-specific protein FSP27”; XP-002133434.
Accession No. AA283696; Strausberg, Robert; “National Cancer Institute, Cancer Genome Anatomy Project (CGAP), Tumor Gene Index” (1997).

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