Chrysanthemyl diphosphate synthase, corresponding genes and use

Details Chrysanthemyl diphosphate synthase, corresponding genes and use Chrysanthemyl diphosphate synthase, corresponding genes and use

1993-06-25

1995-08-22

Furman, Keith C.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

4352402, 4352523, 43525233, 4353201, 536 232, 536 236, C12N 910, C12N 1554

Patent

active

054439787

ABSTRACT:
This invention provides a purified chrysanthemyl diphosphate synthase (CDS), a method for the purification of CDS from Chrysanthemum cinerariaefolium, and an amino acid sequence of the isolated CDS. Also provided is a cDNA encoding the CDS, a nucleotide sequence of the CDS gene, and a derived amino acid sequence of the encoded CDS protein. The CDS gene is useful in the enzymatic production of the natural stereospecific configuration of chrysanthemyl derivatives which are useful for the synthesis of pyrethrins, pyrethroids, derivatives thereof, as well as other classes of metabolites.

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