Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-10-05
1997-12-30
Jones, W. Gary
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 912, 536 231, 536 243, 536 2433, C12Q 168, C12P 1934, C07H 2102, C07H 2104
Patent
active
057028869
ABSTRACT:
To examine the status of chromosome 18q, polymorphic genetic markers and DNA from formalin-fixed, paraffin-embedded tumors are employed. DNA from normal tissue is used as a comparison. The status of chromosome 18q is prognostic of the survival among stage II and stage III colorectal cancer patients.
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Jen et al., "Allelic Loss of Chromosome 18q and Prognosis in Colorectal Cancer", New Engl. J. Med., 331(4):213-221 (1994).
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Hamilton Stanley
Kinzler Kenneth W.
Vogelstein Bert
Jones W. Gary
Rees Dianne
The Johns Hopkins University
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