Chromone derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603452, 424269, C07D40514

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active

039794075

ABSTRACT:
The compound 5,5'-[(2-hydroxytrimethylene)dioxy]bis[2(1H-tetrazol-5-yl)chromone] and non-toxic pharmaceutically acceptable salts thereof.
This compound inhibits the release of spasmogen from antibody-antigen reactions.

REFERENCES:
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patent: 3531493 (1970-09-01), Gittos et al.
Buchanan, et al., J. Med. Chem., vol. 12, pp. 1001-1006 (1969).
Juby, et al., I, J. Med. Chem., vol. 11, pp. 111-117 (1968).
Juby, et al., II, J. Med. Chem., vol. 12, pp. 396-401 (1969).
Stephens, et al., J. Am. Chem. Soc., vol. 77, pp. 1701-1702 (1955).
Mcomie, Advances In Organic Chemistry, Methods and Results, vol. 3, (Interscience Publishers, 1963), pp. 216 and 219-220.

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