Chromogenic tracers for use in an assay

Details Chromogenic tracers for use in an assay Chromogenic tracers for use in an assay

1983-01-24

1984-12-18

Nucker, Christine M.

Chemistry: analytical and immunological testing

Thyroid hormone tests

436537, 436546, 436800, 436811, 436816, 436817, G01N 3352, G01N 3354, B65D 7100

Patent

active

044891652

ABSTRACT:
A chromogen, in particular, a fluorescent compound, is conjugated to a ligand through an amino acid spacer radical, which includes a free carboxyl group. The tracers are particularly suitable for use in a flow through assay for low molecular weight analytes. The tracers are rapidly bound, of good sensitivity, and low non-specific binding.

REFERENCES:
patent: 4166105 (1979-08-01), Hirschfeld
patent: 4171311 (1979-10-01), Araps
patent: 4279992 (1981-07-01), Boguslaski et al.
patent: 4404366 (1983-09-01), Boguslaski et al.
Hassan et al., J. of Immunoassay, 3 (1982) 1-15.
Van Der Werf et al., J. Immunological Meth., 36 (1980) 339-347.
Al-Hakiem et al., Clin. Chem., 28 (1982) 1364-1366.

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