Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-01-29
2008-01-29
Shameem, Golam M. M. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S452000, C548S465000, C514S412000, C514S415000
Reexamination Certificate
active
07323488
ABSTRACT:
This invention provides novel chromogenic enzyme substrates which are indoxyl β-D-ribofuranosides. A process for their production is provided. Methods for detecting β-D-ribofuranosidase activity are given. The advantages of these novel compounds includes: detecting β-D-ribofuranosidase activity with high sensitivity and low substrate concentrations and use with other enzyme indicators in situations where a plurality of enzyme activities is to be visualized simultaneously e.g. for identifying bacteria growth on solid growth media. The synthesis and use of 5-bromo-4-chloro-3-indolyl-β-D-ribofuranoside is exemplified.
REFERENCES:
patent: 5364767 (1994-11-01), Flowers et al.
patent: 6350588 (2002-02-01), Roth et al.
patent: 2 770 538 (1997-11-01), None
patent: WO 97/31008 (1997-08-01), None
Berlin et al (1996): STN International HCAPLUS database, Columbus (OH), accession No. 1996: 734811.
1. Masao Shiozaki , “Synthesis of 4′,8-dihydroxyisoflavon-7-yl D-arabinofuranoside” Exploratory Chemistry Research Laboratories pp. 1477-1742 dated 1999.
2. Berlin et al. XP-002271582 In Situ Color Detection of L-Arabinofuranosidase, a “No-Background” Reporter Gene, with 5-Bromo-3-indolyl-a -L-arabinofuranoside pp. 171-174 (dated 1996).
3. XP-002214084 (abstract only).
4. XP-002214085 (abstract only).
Shameem Golam M. M.
Whitham Curtis Christofferson & Cook, P.C.
LandOfFree
Chromogenic enzyme substrates does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Chromogenic enzyme substrates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chromogenic enzyme substrates will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2811192