Chromium picolinate compositions and uses thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514356, A61K 31555, A61K 3144

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active

059487720

ABSTRACT:
Compositions comprising chromic tripicolinate or chromic polynicotinate in combination with nicotinic acid, picolinic acid or both nicotinic acid and picolinic acid. The compositions may further comprise at least one of a cyclooxygenase inhibitor, an acid and a mucolytic. The compositions are useful for supplementing dietary chromium, lowering blood glucose levels, lowering serum lipid levels and increasing lean body mass.

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patent: 5175156 (1992-12-01), Boynton et al.
patent: 5194615 (1993-03-01), Jensen
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Kamath, et al., Absorption, Retention and Urinary Excretion of Chromium-51 in Rats Pretreated with Indomethacin and Dosed with Dimethylprostaglandin E.sub.s, Misoprostol or Prostacyclin.sup.1,2,3 , J. Nutrition 127:478-482, 1997.
Singh, et al., Pharmacology of an extract of salai guggal ex-Boswellia serrata, a new non-steroidal anti-inflammatory agent, Agents and Actions 18:407-412, 1986.
Coated Pharmaceutical Dosage Forms: Fundamentals, Manufacturing Techniques, Biopharmaceutical Aspects, Test Methods and Raw Materials, CRC Press, Washington, DC, 1998.
Recommended Daily Allowances, Ninth Revised Edition, The national Academy of Sciences, p. 160, 1980.

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