Chromic picolinate treatment

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514866, A61K 31555

Patent

active

050876236

ABSTRACT:
The administration of chromic picolinate, preferably in the form of chromic tripicolinate, as a prophylactic or therapeutic agent for controlling various blood serum parameters. In particular, the administration is for controlling blood serum lipid levels, including the lowering of undesirably high blood serum LDL-cholesterol levels and the raising of blood serum HDL-cholesterol levels. Additionally, the adminstration is for controlling desirable high blood serum glucose levels, this being particularly applicable for the treatment of maturity-onset diabetes. Additionally, chromic picolinate, preferably in the form of chromic tripicolinate, is admistered to facilitate uptake of amino acids by skeletal muscle. Thus chromic picolinate can act as an effective anabolic agent.

REFERENCES:
patent: 2974043 (1991-03-01), Hochberg et al.
patent: 4315927 (1982-02-01), Evans
patent: 4343905 (1982-08-01), Szalay
patent: 4923855 (1990-05-01), Jensen
NIH report Plasma Lipid Distribution in Selected North American Populations.
Abraham, A., et al. Am. J. Clinc. Nutr. 33:2294-2298 (1980).
Anderson, R. Clin. Physiol. Biochem. 4:31-41 (1986).
Anderson, R., et al. Federation Proceedings 43:471 (1984).
Anderson R. "Trace Elements in Health and Disease" Skandia Symposia, Oct. 23-25, 1984, pp. 110-119.
Anderson, R. Am. J. Clinc. Nutr. 36:1184-1193 (1982).
Anderson, R., et al. Metabolism (32(9):894-899 (1983).
Anderson, R. Am. J. Clinc Nutr. 41:571-577, 1177-1183 (1985).
Chen, N. J. Nutr. 103:1182-1186 (1973).
Davidson, I., et al. Proc. Soc. Exp. Med. Biol. 127:66-70 (1967).
Elwood, J., et al. J. Amer. College of Nutr. 1:263-274 (1982).
Evans, G., et al. Biochem. Biophys. Res. Comm. 50(3):718-722 (1973).
Evans, G. Int. J. Biosocial Med. Res. 11(2):163-180 (1989).
Glinsmann, W., et al. Metabolism 15(6):510-520 (1966).
Gonzales-Vergara, E., et al. Israel J. of Chem. 21:18-22 (1981).
Gurson, C., et al. Am. J. of Clinc. Nutr. 26:988-991 (1973).
Haylock, S. J. Inorg. Biochem. 19:105-117 (1983).
Hwang, D., et al. J. Inorg. Biochem. 30:219-225 (1987).
Kidani, Y. J. Pharm. Soc. of Japan 93(9):1269-1273 (1973).
Mirsky, N. J. Inorg. Biochem. 13:11-21 (1980).
Offenbacher, E., et al., Diabetes 29:919-925 (1980).
Offenbacher, E., et al. Ann. Rev. Nutrition 8:543-63 (1988).
Potter, J., et al. Metabolism 34:199-204 (1985).
Press, R. West. Jour. Med. 152:41-45 (1990).
Schroeder, H. J. Nutrition 88:439-445 (1966).
Simonoff, M., et al. Biological Trace Element Research 6:431-439 (1984).
Schwartz, K., et al. Arch. Biochem. Biophys.
Toepfer, E., et al. J. Argic. Food Chem. 25(1):162-166 (1977).
Tuman, R. Diabetes 27:49-56 (1978).
Urberg, M., et al. Diabetes 35:37A Abstract No. 147 (1986).
Yamamoto, A. Toxicology and Applied Pharmacology 59:515-523 (1981).
Yamamoto, A., et al. Jour. of Inorg. Biochem. 22:91-102 (1984).
Toepfer, E. W. et al., J. Agr. Food Chem. 21(1):69-73 (1973).
Abraham, A. et al., The Amer. J. of Clin. Nutri. 33:2294-2298 (1980).
Press, R. I. et al., Western Journal of Medicine 152:41-45 (1990).
Evans, Gary W., International Journal of Biosocial and Medical Research 11:(2):163-180 (1989).
Nutrition 21 consumer education brochure: "The Prophylactic and Therapeutic Potential of Chromium Picolinate in Diabetes, Hyperlipidemia, Anabolism and Weight Reduction" (1989).
Present Knowledge in Nutrition, 5th Ed. The Nutrition Foundation (1984) pp. 571-582.
Boyle, et al., (1977) Southern Med., Jour. 70:1449-1453.
Riales, R., in Chromium in Nutrition and Metabolism (Shapcott and Hubert, Eds., 1979) pp. 199-212.
Newman, H. A. I. et al., (1978) Clin. Chem. 24:541-544.
The Lipid Research Clinics Coronary Primary Prevention Trial Results, (1984) J.A.M.A. (J. Amer. Med. Assn.) 251-351-364.
Recommended Dietary Allowances, 9th Revised Ed. The National Academy of Sciences (1980) pp. 159-161.
Albers, J. J. et al., (1978) Clin. Chem. 24:853-856.
Friedewald, W. T., (1972) Clin. Chem. 18:499-502.
Naito, H. K., (1986) J. Clin. Immunoassay 9:11-20.
Clegg, M. D. and Schroeder, W. A., (1959) J. Amer. Chem. Soc. 81:6065-6069.
Hills, M. et al., (1979) Brit. Jour. Clin. Pharmacol. 8:7-20.
Newman, W. P. et al., (1986) New England J. of Med. 314:138-144.
Avogaro, P. et al., (1978) Artery 4:385-394.
Sniderman, A. et al., (1980) Proc. Natl. Acad. Sci. U.S.A. 77:604-608.
Riesen, W. F. et al., (1980) Atherosclerosis 37:157-162.
De Backer, G. et al., (1982) Atherosclerosis 42:197-203.
Maciejko, J. J. et al., (1983) New Engl. J. Med. 309:385-389.
Schmidt, S. B. et al., (1985) Am. J. Cardiol. 55:1459-1462.
Kwiterovich, P. O. et al., (1983) Preventive Medicine 12:815-834.
Brunzell, J. D. et al., (1984) Atherosclerosis 4:79-83.
Schaller, K. H., (1973) At. Absorption Newsletter 12:147-150.
Evans, G. W., (1980) Pediatric Res. 14:876-880.
Mertz, W., Nutrition Reviews 33(5):129-135, see also Abstract citations 2535 and 2537.
Seal, C. J. and Heaton, F. W., (1983) Brit. Journal of Nutrition 50:317-324.
Chemical Abstracts citation 88:163086, (1977).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Chromic picolinate treatment does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Chromic picolinate treatment, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Chromic picolinate treatment will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-782030

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.